Monday, August 24, 2020

Critical Study of Nutrient Sensing and Root System Architecture (Arabidopsis Thaliana) The WritePass Journal

Basic Study of Nutrient Sensing and Root System Architecture (Arabidopsis Thaliana) 1. Presentation Basic Study of Nutrient Sensing and Root System Architecture (Arabidopsis Thaliana) 1. Introduction2. Issue Statement Root System Architecture  Arabidopsis ThalianaEZ-Rhizo3. Foundation Survey Development LanguageDrawing packagesJava 2DOpenGLFractal DimensionAlpha BlendingVisualization Uncertainty 4. Proposed ApproachBasic FunctionalityAdditional FunctionalityDesign MethodologyRisk Analysis5. Work Plan Background ResearchRequirements Capture Implementation of the Basic FunctionalityTesting of Basic FunctionalityDesign and Build PrototypesExperiments with PrototypesIntegrate wanted Prototypes Testing of Additional FunctionalityComplete and Submit DissertationBibliography Related 1. Presentation In 2004, the United Nations distributed a report (United Nations, 2004) anticipating that the world’s populace would consistently build, year on year, until at any rate 2050. Somewhere in the range of 2004 and 2010 the world’s populace expanded by 5 million individuals (PRB, 2004 and PRB 2010), showing the legitimacy of this expectation. A year ago, the United Nations (United Nations, 2010) distributed another report assessing that more than 900 million individuals were all the while experiencing malnourishment, featuring a deficiency inside the volume and conveyance of food right now being produced.â As an outcome, it has as of late been recommended that as the populace develops the quantity of individuals confronting food instability will likewise expand (Den Herder et al, 2010), except if the weights influencing food creation can be mitigated. To expand the volume of food being created, researchers have instructed that at any rate one with respect to the accompanying targets must be accomplished (Godfray et al, 2010): Improve the amount and nature of yield reaping Recognize or make progressively arable (land that can be utilized for developing yields) By expanding the amount of the food we produce we ought to hypothetically have the option to take care of the developing populace. As of late the utilization of manures and pesticides have been utilized to improve the quality and amount of the yields anyway utilization of this can't be expanded because of the dangers to general wellbeing (Den Herder et al, 2010), thus different alternatives must be investigated. Researchers are examining techniques with which to advance a plant’s admission of supplements and to build their resilience against threatening ecological conditions, for example, dry season. Another territory researchers have been investigating is that of how to change over land that would be viewed as unsatisfactory for plant development (Den Herder et al, 2010). By discovering more land on which to develop crops, we could create more produce utilizing our current methods. There is broad research being directed in both of these zones anyway this task might be focussing on the work being contributed by the Plant Science Group.  This Group are a piece of the Institute of Molecular, Cell and Systems Biology inside the College of Medical, Veterinary and Life Sciences at the University of Glasgow.â The Plant Science Group comprises of more than 50 dynamic researchers, of which Dr Anna Amtmann is at present a Research Group Leader, and their work covers a scope of points from plant sustenance to plants impact on human metabolism.â Within the Plant Science Group, Dr Amtmann’s Research Group is directing examination into the plant Arabidopsis Thaliana, with the point of â€Å"understanding the sub-atomic components required inside (Amtmann, 2011)†: Supplement utilization productivity Salt and dry spell resistance Connection among abiotic and biotic pressure To accomplish this understanding test explore is being led in various regions by her group, and this task plans to help the work inside Nutrient Sensing and Root System Architecture. This exploration includes developing Arabidopsis Thaliana in controlled ecological conditions and investigating the impact on the plants by checking their individual root structures. By looking at root framework structures that have created in various natural conditions, explicit qualities can distinguished which can prompt the comprehension of how plants consumption various supplements and react to explicit burdens. Presently, the group grows many examples Arabidopsis Thaliana and records data about every one of their root framework structures. This outcomes in huge volumes of information that require investigation and documentation. As of now the group make diagrams to picture and investigate this information yet they have as of late educated with respect to the unacceptability of this approach.â This is transcendently because of the constrained perception choices of charts when considering root parameters and the way that charts can very tedious to develop. Consequently, this task plans to build up a framework that will permit Dr Amtmann’s Research Group to envision root framework designs of Arabidopsis Thaliana by utilizing procedures that will control the root structure engineering information into intriguing and justifiable portrayals. The accompanying sections of this proposition intend to report the proposed work that will be attempted in an ace undertaking that will accomplish this point. 2. Issue Statement Because of the organic idea of this task, this area will characterize various key ideas required to comprehend the work embraced by Dr Amtmann and her partners, and the issues they face, before talking about the expectations of this venture. Root System Architecture Dr Amtmann’s group evaluates the root framework models of Arabidopsis Thaliana to see how ecological conditions influence its turn of events. The root arrangement of a plant is liable for the admission of water and sustenance (Malamy, 2005), among other basic capacities, thus assumes a significant job inside the advancement of any plant.â The root framework regularly comprises of a primary root with various parallel branches, which contain various root hairs that are answerable for the take-up of supplements and water (Wikipedia, 2011). The manner by which these fundamental roots extend and branch is viewed as the root framework engineering (RSA) (Figure 1). Contingent upon the earth in which a plant dwells, changes happen to the RSA that can significantly affect the water or supplement take-up of the plant(Armengaud et al, 2009). Consequently by understanding the ecological conditions that advance the development of a fruitful RSA we can guarantee the improvement of a sound plant. Figure 1 †Root Structure Architecture (RSA) taken from â€Å"Root-System Development and Water-Extraction Model Considering Hydrotropism† by D. Tsutsumi et al.  Arabidopsis Thaliana In the same way as other research ventures, Amtmann’s bunch utilizes the plant Arabidopsis Thaliana inside their examinations. Arabidopsis Thaliana is viewed as a model animal varieties inside plant science and science as its genome was sequenced in 2000, implying that its total DNA grouping was resolved (Wikipedia, 2011).â As the genome is moderately little it is simpler to work with and dissect. It is additionally firmly identified with an enormous number of different plants, for example, (Somerville and Koorneef, 2002) implying that any finding could be broadly material. It can likewise be handily developed in research facility conditions because of its little size and clear development conditions. Because of the Arabidopsis Thaliana sequenced genome, researchers can figure out which hereditary blends are liable for specific qualities of the plant, for example, the bearing of root development or number of horizontal branches.â Figure 2 features some variety in foundations of Arabidopsis Thaliana. Figure 2 Different Root Structure Architecture for Arabidopsis taken from unil.ch/dbmv/page36242_en.html Right now Dr Amtmann’s bunch develops different examples of Arabidopsis Thaliana in square agar plates that permit them to take two-dimensional pictures of the plant roots as it grows.â These pictures are then analyzed utilizing a bespoke framework called EZ-Rhizo, which was created by Dr Amtmann’s Research Group, to decide the RSA of the plant. EZ-Rhizo EZ-Rhizo is uninhibitedly accessible programming that recognizes and gauges the RSA of a plant rapidly and precisely (Armengaud et al, 2009) when provided with a picture of a root framework. It was created by Dr Amtmann’s Research Group related to college understudies from l’Ecole Supã ©rieure dIngà ©nieurs en Electrotechnique et Electrique in 2008.â The principle capacity of the framework is to quantify data about the fundamental root and the horizontal underlying foundations of a plant, and record this. Every numerical worth are put away in centimetres.â It at that point utilizes this information to determine further parameters, for example, the apical zone or straightness of the root. The key parameters that are caught by EZ-Rhizo according to this venture are as per the following: Apical Zone, which is the length of the root between the highest point of the fundamental root and the most seasoned parallel root Length, which is the all out length of the root from the beginning of the principle root to the tip of it.â (Note that as roots don't develop straight this worth might be extremely huge yet the root might not have developed that far towards the ground) Vector Length, this is like the length anyway it compute the most brief conceivable length of the root beginning from the birthplace of the primary root to its tip. Straightness, which is the Vector Length, isolated by the Length. Point, which is the degree between the Vector of the root and complete verticality. A full posting of all the parameter catch by EZ-Rhizo can situated in the in that’s distribution The framework was created for the Microsoft Windows working framework and stores information in a MySQL database. Questions would then be able to be submitted to the database, which will recover the entirety of the put away information for a predetermined root and out

Saturday, August 22, 2020

Definition and Examples of Tmesis

Definition and Examples of Tmesis Tmesis is the division of the pieces of a compound word by another word or words, for the most part for accentuation or comic impact. The descriptive word structure isâ tmetic. Identified with tmesis is synchesis, the disordering of word request in an articulation. Etymology: From the Greek, a cutting Pronunciation:â (te-)ME-sister Additionally Known As: infix, tumbarumba (Australia) Models and Observations Abso-mother truckin' lutely! I said triumphantly as I intellectually crossed my fingers. (Victoria Laurie, A Vision of Murder. Seal, 2005)Goodbye, Piccadilly. Goodbye, Leicester wicked Square. (James Marsters as Spike in Becoming: Part 2. Buffy the Vampire Slayer, 1998)Whoopdee-damn-doo, Bruce thought. At most papers, general task journalists were newsroom sovereignty, given the most significant stories. At the East Lauderdale Tattler, they were an indent above janitors, and troubled with humble assignments . . .. (Ken Kaye, Final Revenge. AuthorHouse, 2008)To convince individuals to continue viewing [the TV program Zoo Quest], [David] Attenborough gave the arrangement a goal, an uncommon creature to seek after: picarthates gymnocephalus, the bare headed stone crow. He questioned this animal would be sufficiently appealing, however when his cameraman Charles Lagus was driving him down Regent Street in an open-top games vehicle and a transport driver inclined out of his taxi and solic ited, in a slick bit of tmesis, on the off chance that he was ever going to get that Picafartees gymno-bleeding cephalus, he realized it had stopped itself in the open psyche. (Joe Moran, Armchair Nation. Profile, 2013) This isn't Romeo, hes some other where. (William Shakespeare, Romeo and Juliet)In what torn boat soever I embark,That transport will be my emblemWhat ocean soever swallow me, that floodShall be to me a seal of thy blood. (John Donne, Hymn to Christ, at the Authors Last Going Into Germany)Most frequently, tmesis is applied to mixes of ever. What direction so ever man allude to it (Milton); that manhow profoundly ever separated (Troilus and Cressida 3.3.96); how shocking eer it be,/To win thy after-adoration I pardon thee (Richard II 5.3.34). In any case, the syllable of any word can be isolated: Oh so beautiful sitting abso-blossoming lutely still (A. Lerner and F. Lowe, My Fair Lady). Or then again See his windlilycockslaced (G.M. Hopkins, Harry Plowman). Tmesis is additionally normally utilized as far as British slang, for example, hoo-wicked beam. (A. Quinn, Tmesis. Reference book of Rhetoric and Composition, ed. by T. Enos. Taylor Francis, 1996)Its a kind of long cocktailhe got th e recipe off a barman in Marrakesh or some-grisly where. (Kingsley Amis, Take a Girl Like You, 1960) I summoned up the mental fortitude to jab a camera through Terry Adamss front door a year ago, just to be met with a minders welcoming: Why dont you leave us a-f-ing-solitary. I wonder if the savage knew about his utilization of tmesis, the inclusion of single word into another? (Martin Brunt, How Terror Has Changed the Crime Beat. The Guardian, Nov. 26, 2007)old age sticksup KeepOffsigns) youth yanks themdown(oldagecries NoTres) (pas)youth laughs(singold agescolds Forbidden StopMustnt Dont) youth goesright ongrowing old(E.E. Cummings, mature age sticks)Gideon [Kent] knew [Joseph] Pulitzer, obviously. He appreciated the distributers request that his paper never become the hostage of any gathering or ideological group. Indegoddamnpendent was Pulitzers one of a kind method of putting it. (John Jakes, The Americans. Nelson Doubleday, 1980) Tmetic Rhythms At the point when you embed a word for accentuation be it fricking, bleeping, something ruder, or something less inconsiderate you cant simply stick it any old where. We know this in light of the fact that abso-cracking lutely is fine however stomach muscle cracking solutely or outright cracking ly isn't. Regardless of whether its in a word, an expression, or a name-you stick the insistent expansion directly before a focused on syllable, as a rule the syllable with the most grounded pressure, and regularly the last focused on syllable. What were doing, in prosodic terms, is embeddings a foot. . . . With regards to putting these additional feet in, we ordinarily break the word or expression as per the musicality of what were embeddings. Regarding life, what to think about it, that is the issue is thought of as measured rhyming, however you wont break it between iambs if your intruding by walking is a trochee: To be or not to bleeping be, not To be or not bleeping to be . . . Be that as it may, if its an iamb? To be or not the hell to be, not To be or not to the hell be. See, these are impolite, intruding on words. Theyre breaking in and destroying the structure. That is the cracking point. Be that as it may, they despite everything do it with a musical inclination. (James Harbeck, Why Linguists Freak Out About Absofreakinglutely. The Week, December 11, 2014) The Split Infinitive as Tmesis A split infinitive has been somewhere else characterized as a kind of syntactic tmesis in which a word, particularly a qualifier, happens among to and the infinitival type of an action word. Various marks have been utilized to name this specific requesting of English, spiked qualifier or parted infinitive among others, yet the term split infinitive has in the end supplanted every one of its antecedents (Smith 1959: 270). (Javier Calle-Martin and Antonio Miranda-Garcia, On the Use of Split Infinitives in English. Corpus Linguistics: Refinements and Reassessments, ed. by Antoinette Renouf and Andrew Kehoe. Rodopi, 2009)

Thursday, July 23, 2020

Best Retirement Plans For Entrepreneurs

Best Retirement Plans For Entrepreneurs © Shutterstock.com | pathdocIn this article, we discover 1) an introduction to preparing for retirement for entrepreneurs, 2) the importance of retirement planning for entrepreneurs, 3) most popular retirement plans for entrepreneurs, and 4) how entrepreneurs can plan for retirement.INTRODUCTIONA retirement plan is an investment and savings plan that would provide you with enough income to live independently after retirement. Against common perception, even entrepreneurs can have retirement plans and make their life as easy as possible after retirement. You, as an entrepreneur, might provide retirement plans for your employees, but you must consider choosing a good retirement plan for yourself as well.A retirement plan often includes identifying income goals after retirement as well as decisions and actions to attain those goals. The plan further includes managing assets, implementing a savings program, estimating expenses and determining the source of income necessary for you to li ve without any financial woes after you have retired. Similarly, you also need to estimate future cash flows in order to ensure that you do achieve your retirement income goals.As mentioned above, it is totally false on your part to think that retirement plans are only for government workers, police officers or teachers, etc. You need to think again. These are definitely the most common types of retirement plans, but there are many other types of plans that have been devised especially for entrepreneurs like you.For example, I always recommend a Simplified Employee Pension Individual Retirement Arrangement (SEP-IRA), one of the most common types of IRAs available to entrepreneurs in the United States. There are negligible administration costs if you happen to be a solo entrepreneur. If you have people working for you, all of you will receive the same SEP benefit.Today, most entrepreneurs like to work beyond the typical retirement age. However, adequate financial planning for the lon g run can provide you with enough flexibility and control when you do decide to hang up your boots.IMPORTANCE OF RETIREMENT PLANNING FOR ENTREPRENEURSIt is absolutely essential for you to take your retirement in your own hands and plan well in advance to enjoy a financially secure retirement. Here are some reasons why you need to plan for retirement:You Can’t Rely on the Government Welfare System: Although the government sponsors your retirement, it is not enough to meet your financial requirements once you retire. You need to remember that the ratio of covered workers to the number of beneficiaries has decreased significantly over the last few years. Similarly, people are living longer than ever before due to advances in healthcare. As a result, there is a greater strain on resources and governments nowadays have no other option but to reduce social security benefits.Find Possible Sources of Income Now: It is necessary for you to find all possible sources of income when you are s till in control, to financially secure your post-retirement life. Once you retire, it will be difficult to maintain your current lifestyle as social security will replace only a fraction of the money you are earning while working. You have to supplement social security benefits by investing in retirement plans such as a 401(k), Individual Retirement Agreement Accounts, and other securities.Increasing Life Expectancy: Due to tremendous advancements in healthcare, people are living longer these days. Therefore, it is even more important for you to arrange enough financial resources to support yourself. It is also a bad idea to save only enough to last to a certain age. What if you live beyond that age? In this case, you might struggle to fund the “extra years” of your life. Therefore it is imperative for you to plan to live beyond the average life expectancy.Unexpected Medical Expenses: It is never the best option to rely on funds that you cannot control. Frequent health problems and increased medical expenses are an integral part of old age. If you don’t have adequate funds to cover these expenses, the golden years of your life may also become a nightmare because social security will only cover the bare minimum of your expenses. In this case, investing in long-term healthcare medical insurance can help you to prevent a lot of problems in the long run.Flexibility to Take Future Challenges: Life is full of surprises and unforeseen difficulties such as the deteriorating health of your loved one, a crumbling social security system and growing financial needs of your dependents. However, you will do yourself a big favor if you have secured enough to meet all of your future requirements without any hassle. This will provide you with peace of mind when you need it the most.Money Depreciates in Value: Considering the current inflation rate, the value of money is going to decrease considerably, say in next 30 years. Unless you plan properly, your buying and sellin g power will not be the same as it is today. It is important for you to recognize the true potential of saving in future terms if you don’t want to ruin your last years of your life struggling with financial problems.MOST POPULAR RETIREMENT PLANS FOR ENTREPRENEURSAs an entrepreneur, it is your own responsibility to determine what type of retirement plan suits your particular requirements. It can be a bit confusing because there are plenty of options to choose from. In this regard, following are some of the most comment retirement plans you might consider.The Small Business or Self-Employed 401(k)A 401(k) is perhaps the most popular retirement plan not only among employees, but entrepreneurs as well. All the big banks in the United States offer different variations of this very plan such as the self-employed 401(k) or small business 401(k). In simple words, a 401(k) is all about investing a portion of your income in a mutual fund. There is a pool of management investments or contri bution that helps your investment grow over time.You can slightly reduce your tax burden as all the contributions are pre-taxed based. The major difference between self-employed and small business plans is that the former does not have any set up fee. For small business plans, set up fees are scaled to the size of your business and they cover multiple employees. Similarly, your selected institution will handle distribution of the profits and tax advisory services.Simple IRA PlanIf your company has less than 100 employees, you might consider a Simple Individual Retirement Account (IRA) plan. Contributions are mostly done in the form of payroll deductions before the tax is paid. This plan requires both the employer and the employees to contribute some portion of their salary from each paycheck.You, as an employee, must make a matching contribution dollar for dollar, and it can be up to 3% of the compensation you pay to an employee. On the other hand, you can make a fixed contribution for all eligible employees even if they don’t contribute to the plan. This contribution can be up to 2% of their respective compensations. You can include all new employees in this plan without their consent but must also give them the option to opt out.There are many institutions across the country which can help you to establish a simple IRA for your business. Similarly, if you are already dealing with a certain bank, they might also have provisions to set up a simple IRA for you.Retirement-Oriented Profit SharingRetirement-oriented profit sharing is an option for you if you cannot afford the fees of the 401(k) or you are not sure whether your business requires a simple IRA or not. The discretionary nature of the profit sharing plan also gives you the liberty to set any threshold level in terms of how the plan will be kicked in and how the profits will be distributed.Most profit sharing plans are launched at the end of the fiscal year when all the expenses have been calculated. This simply means that you will not be working with pre-tax gross but have to deal with post-tax net profit. Profit sharing plans can reduce your saving efficiencies and increase tax expenses, but it will make employees feel more empowered to achieve the organizational goals as well.Simplified Employee Pension (SEP) PlanYou can set up SEP-IRAs for all of your employees and yourself through a Simplified Employee Pension (SEP) plan. You have to make a uniform contribution for each of the employees, but it is not compulsory to make a contribution every year. If you automate the contributions and define them well, the pension plan can work perfectly both for you and your employees. In fact, missing a contribution to the SEP can also be an advantage for you, especially if your company is having a really bad year.Again, almost all large financial institutions provide the facility of SEPs but its forms are a bit more complex as compared to IRA plans. Advisory services and fees vary from in stitution to institution. It is also pertinent to note that you are not bound to make any contribution as a package deal because this is essentially a pension plan. You must take a good look at the plans and make a decision accordingly. However, you have to maintain transparency so everyone knows what the scope of the pension plan is and how it is going to help them.Individual Pension Plan (IPP)More and more entrepreneurs are investing in Individual Pension Plans nowadays. Essentially a type of Defined Benefit Pension Plan, IPP helps you to secure your retirement in addition to increasing your tax-deferred retirement plan contributions. You make contributions according to a set formula based on the total years of your services and your age.The first year contribution can be as big as $40,000 where your company has to contribute most of the money. However, this type of plan is well-suited to rich businessmen only because the annual contributions are $100,000 or more. The good thing i s that the amount paid by the company will decrease as the contribution is a tax-deductible expense.Insured Retirement Plan (IRP)I would also suggest you try an Insured Retirement Plan, especially if you are still 10-15 years away from retirement. Similarly, if you are looking to acquire life insurance, it is better to invest in an insured retirement plan rather than choosing traditional insurance. As a matter of fact, insured retirement plans offer additional income through a life insurance that is, of course, exempted from all kinds of taxes. This type of retirement plan can also be a great option for you if you are already maximizing your contributions to Registered Retirement Saving Plans (RRSP).Retirement Compensation Agreement (RCA)You can also invest in the Retirement Compensation Agreement for the welfare of key employees of your company, including yourself. As the name suggests, RCA is a sort of agreement in which an organization makes a contribution to a third party that i s commonly known as a custodian. These contributions are later delivered to the employee at the time of his retirement or termination.As compared to other retirement plans discussed above, RCA is rather complex and unsuitable for every entrepreneur. However, it has certain benefits such as it helps you to avoid valuation requirements as in the case of IPP. Similarly, the tax will not be deducted from the contribution until the employee receives the benefits.Money-Purchase Pension Plan (MPPP)Both you and your employees make contributions to a Money-Purchase Pension Plan according to the terms of the agreement where the contributions are based on annual salaries. You can purchase a sort of allowance for your lifetime at the time of your retirement using the total pool of capital in your account. Obviously, the amount of capital varies from member to member based on their level of contribution and return on investment of those contributions. An MPPP depends upon your employees to ensur e adequate levels of retirement income for all the members including the employers.HOW ENTREPRENEURS CAN PLAN FOR RETIREMENTThere is nothing wrong in saying that most entrepreneurs lose sight of their retirement goals because they have so many duties to perform. However, there are many things you can do to make your retirement smooth and hassle-free as explained below.Save Money for RetirementYou must start saving a substantial amount of money for your retirement right now because saving for retirement is not a sprint but a marathon. There are many businessmen who invest all their resources, energy and money back into their business and cut a sorry figure when they retire. You should not repeat this mistake as it is vital to start saving as soon as possible.Choose a Retirement PlanOne of the easiest methods of saving money for retirement is to invest in a retirement plan. There are plenty of retirement plans for entrepreneurs, and you can choose one depending upon your particular re quirements, obligations, and investment limits. Investing in a retirement plan of your choice is a decision will not regret.Groom a Worthy SuccessorIt is never a wise idea to postpone the creation of a succession plan. Just like the retirement plan, you should start formulating a succession plan as early as possible even if your retirement is decades away. Grooming a worthy successor, whether it is your son, daughter or anyone else, means you and your business will always remain in good hands.Formulate a Realistic Retirement StrategyYou should have a good idea about how many more years you want to work or when you are going to retire. You should not put off your retirement plan because retirement often comes earlier than you expect. Put all your requirements and ideas in black and white, as it will make things smoother for you. Do all things legally to make sure that you don’t jeopardize your retirement.Prepare a Good Tax StrategyThere are many things you need to beware of when pl anning for retirement and the most important of them is the tax implications. For instance, you are eligible for a capital gains exemption (up to $70,000) if you are selling your business. It is always better to work with a trusted legal professional to better understand tax requirements and how to meet them.Identify Sources of Your Retirement IncomeIt is foolish to think that you will fund your retirement simply by selling your business. The value of a business can depreciate over time or you may even decide to pass on the business to your heir. What you will do if anything like this happens? Similarly, money received from social security is never enough to live a post-retirement dream life. Therefore, it is important for you to identify all sources of income that can fund your retirement and make it pleasant rather than a nightmare.Your business is just like your child, and it is always difficult to bid farewell to someone you love so dearly. It is a herculean task to set up a suc cessful business, and it is even more difficult to sell it or pass it on to someone else. However, you have to go through this ordeal one day, and you can make the transition as smooth as possible with some careful retirement planning.

Friday, May 22, 2020

Facing the Death of a Beloved Person - 933 Words

Facing the Death of a Beloved Person There are several ways to respond to the loss of someone when the time has come to say goodbye. People sometimes can choose between bad or not so bad reactions, but at the end, it is all about how to deal with the fact that their loved one won’t be by their side anymore. However, there will be situations in which the easiest answer is to say â€Å"everything will be fine†, but is that what people really mean in the tough moments? The issue of death is approach by several artist including writers as a controversial topic. In the two works studied â€Å"The story of an hour† by Kate Chopin and â€Å"One art† by Elizabeth Bishop is impressive how ironically the reactions can be misinterpreted by the readers who might think that death would be a disaster or maybe not for the two women who have lost a beloved person. Kate Chopin writes in her short story about Louise Mallard’s reaction to her husband’s unexpected death. After Mrs. Mallard hearing the news, she wants to be alone in her room. She apparently reacts as typically as someone who has lost an important part of her life, running to an empty room with any future expectations. For everyone, it appeared that she is devastated because of her lost. However, once Louise is in her room, the reader realizes the real meaning of her emotions. When she whispers: â€Å"Free, free, free!†(Chopin, 67) is obvious that she is not sad at all; it can be interpreted as freedom instead. She sounds relieved of not having herShow MoreRelatedComparing Shakespeares Shall I Compare Thee to a Summers Day and Burns A Red Red Rose1154 Words   |  5 Pagesof instilling in the reader the impression of their love and in explaining the depth of their emotion for the beloved as well as the respective poets ideas about the very nature of love and h ow it can be both passionately fulfilling and devastating. 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I will use the four arguments presented by Barzun to support my thoughtsRead MoreA Hero s Tragedy : A Critique On The Film Fury Using Aristotle s Principles Of A Tragedy1219 Words   |  5 Pagesoverall good nature. â€Å"The best type of hero; exist between the extremes†¦ a person who is neither perfect in virtue and justice† (Othello and the Aristotle Tragedy). Cummings states that Aristotle believes a tragic hero/ protagonist should be a person who does not befall every misfortune, but is not an perfect human either; this is due to, the fact it makes the hero more relatable as they appear to the audience as an actual person, possibly one they could be. Fury will follow this statem ent of Aristotle’sRead MoreOn The Fear Of Death By Elizabeth Kubler Ross1346 Words   |  6 PagesThere is huge difference between Death and Dying. Death is the end of life, while dying is the process in which you death, also including the choices and actions involved in that process. In â€Å"On the Fear of Death,† by Elizabeth Kubler-Ross she describes the different aspects of dying, the final days of individuals who are terminally ill, the grieving process, and how children are treated during the time of death. The dissimilitude in â€Å"old-fashioned† death and â€Å"modern† final days are presented. SometimesRead MoreAbolish The Death Penalty Should Not Be Abolished1592 Words   |  7 PagesLaudani Composition 1 09 July 2015 Abolish the Death Penalty Since the state has no power to give life, it should not exercise its power to take a life either. After all, the judicial system is not a fool-proof system. The risk of putting an innocent human being to death by capital punishment, cannot be ruled out. The only purpose it serves is retribution or revenge. Therefore, the death penalty must be abolished. The death penalty is prone to errors that may have led to the executionRead MoreFacing the Truth Essay1418 Words   |  6 PagesFacing the Truth Should people always tell the truth, or it is sometimes better to lie? Some people prefer to hide themselves behind a wall of lies rather than face the truth and deal with it. It is an incontestable fact that truth hurts, but without it people can never create trustful relationships or reach real happiness. This can be observed in families relationships. Every family has secrets that remain hidden somewhere in the deepest drawers; secrets that people keep in order to protect

Thursday, May 7, 2020

The Eradication Of Cancer And Cancer Essay - 1118 Words

1.1. Introduction Eradication of cancer is one of the key challenges for medicine in the 21st century, breast cancer being the most common type of cancer in women, worldwide (Arteaga and Baselga, 2012, Vidal et al., 2012 and Weinstein et al., 1997).Breast cancers are classified on the basis of expression of hormone receptors i.e., Estrogen receptor, Progesterone receptor and HER2. The subtypes are as follows: †¢ Luminal tumors (HR +) †¢ HER2 amplified tumors †¢ Triple negative breast cancer tumors (TNBC) Approximately, 10-15% of breast cancer cases are accounted by triple negative breast cancer. These tumors are characterized by the absence of ER, PR and HER2. Chemotherapy, therefore, is the only systemic option for patients with TNBC. (Twelves C et al, 2016 and Banerji et al.,2012) 1.2. Comparison of 2D and 3D (spheroid) cancer models on the basis of their drug screening ability Several studies have shown the use of 2D cancer models to identify the efficacy of a particular drug. However, these cancer models have limited predictive value to show a realistic stimulation of in vivo tumor microenvironment. This is due to large differences in physiological conditions as well as morphology between 2D cancer models and in vivo tumors. Factors such as therapy resistance, drug transport and binding, cell invasion and migration of tumors cannot be effectively studied in vitro with the use of these cancer models. Hence, selecting a clinically active drug is a challenging task when 2DShow MoreRelatedTobaccos Harmful Effects, Health and Economic Essay1334 Words   |  6 Pagesand Malaria combined, according to International Union Against Cancer. This addicting drug can in fact end up giving the user a death sentence. As the body grows older, the DNA atoms can be mutated by this seemingly harmless plant. This mutation of cells can eventually spread and the user will end up with a body full of cancer. These cancer sticks or cigarettes are not only harmful to your body but also hard on your wallet. The eradication of the use of tobacco would deplete the health risks associatedRead MoreHelicobacter Pylori And Gastric Cancer2702 Words   |  11 PagesHelicobacter pylori and Gastric cancer Helicobacter pylori is a small, microaerophilic gram negative rods that regularly colonize the human stomach (Strausbaugh et al., 2002). It is one of the common bacterial pathogen that is found in the stomach of almost half of the world’s population (Zhao et al., 2014) and such well adaptation or successful long lasting colonization of H. pylori in to the human stomach is achieved by the combination of different factors, which addresses different challengesRead MoreA Theory of the Cause of Skin Cancer Essay1642 Words   |  7 PagesA Theory of the Cause of Skin Cancer This theory of cancer was presented in detail in the book One Answer to Cancer by Dr William Kelley, although certain adaptations have been made. You would be well served to look at the original book available for free on the internet. According to the theory, a person cannot have cancer unless three factors are present. These three factors are: (I) The presence of a certain type of cell that becomes genetically damaged. In theRead MoreDDT Isnt Cool With Me Essay1539 Words   |  7 Pagesmalaria eradication plans including the use of mosquito nets and pesticides. These eradication plans cornerstone is through its aggressive attempt to rid the area of the anopheles mosquito, thus virtually eliminating the spread of malaria and cases seen. The parasites that cause malaria rely on a human host in order to reproduce and thrive. The vector, mosquitos in this case, are simply the means by which the parasite finds its next human host to thrive again. As seen by the eradication of malariaRead MoreEfficient Delivery Of Cancer1418 Words   |  6 Pagesto tumors faces several difficulties and obstacles that need to be overcome for effective cancer treatment. Nanoparticles administrated through intravenous injections accumulate at a tumor site due to the enhanced permeability and retention (EPR) eï ¬â‚¬ect, but only a small quantity of the injected particles can actually â€Å"reach the tumor† (Su et al, 2016). The majority of the nanoparticles interact with â€Å"cancer cells at the periphery of a tumor† which presents a â€Å"physiological barrier† that preventsRead MoreThe Effects Of Helicobacter Pylori On The Human Stomach2999 Words   |  12 Pagesknown as causative agent of variety of gastric or s tomach disease such as gastro-duodenal ulcer and gastric cancer and the most common (gastritis) in human (Backert et al., 2004). Among all such stomach diseases, the linkage between H.pylori and gastric cancer has become the subject of interest between all of the people around the world because in 1994 an â€Å"International Agency for Research on Cancer† (IARC) that is also known as subordinate organization of WHO identified H.pylori as group 1 â€Å"definiteRead MoreThe First Major Discoveries That Laid The Foundation For Technological Advances During The World Of Vaccinations1364 Words   |  6 Pagesintroducing cowpox and rabies into the two boys. It was building and preparing their bodies for war against the actual disease. Another great discovery was made in HeLa cells. Taken from a tumor of Henrietta Lacks when she was diagnosed with cervical cancer, her cells were the first to be cloned outside the body successfully. She is the immortal soul that keeps giving. Her cells were used to help create a vaccine for polio and are still being used for research today. New technology allowed for furtherRead MoreStem Cell Classification Essay1326 Words   |  6 Pagescollectively coming with the proper direction to make it possible. Cures and Eradication for Diseases Stem cell research advances have led to cures and eradication of many life-threatening, chronic and debilitating diseases and conditions. Stem cells have the capability to divide and renew for long periods of time and can produce specialized cells. The ability of stem cells to produce more specialized cells is called differentiation. Cancer treatments currently result in considerable loss of healthy tissueRead MoreThe Anti Vaccine Movement And The Vaccine1620 Words   |  7 Pagesvaccinations. Firstly, eradication is a primary goal of all immunization programs; however, only smallpox has been eradicated to date. Eradication requires high levels of population immunity all over the world for a prolonged period of time. The World Health Organization reports that the next disease targeted for eradication is polio (Andre, Booy, Bock, Clemens, Datta, John, Lee Lolekha, 2008). Secondly, elimination of a disease locally is possible without the eradication of a disease worldwideRead MoreBr east Cancer : Cancer And Cancer946 Words   |  4 PagesSkylar Steinman Period 6 Ms. Jobsz 12 February , 2016 Breast Cancer It is commonly known that Breast Cancer is one of the most insidious diseases that mankind has had to deal with. With the discovery of the BRCA1( BReast Cancer gene one) and BRCA2 (BReast Cancer gene two) genes, breast cancer can be detected with a great amount of certainty on a genetic level in some women and men. 40,000 women and men die of breast cancer each year. Knowing this it is very important to try to detect the mutation

Wednesday, May 6, 2020

Unit 7 †Childcare and Education Level 3 Cache Free Essays

string(107) " of information from agencies outside the settingwhich may contribute to the assessment of learning needs\." E1 Collate evidence which describes the role of the practitioner in meeting children’s learning needs. Gather and present information about the role of the practitioner whenchildren’s learning needs. A practitioner’s role in meeting children’s learning needs are to understand and work with each and every child’s learning needs. We will write a custom essay sample on Unit 7 – Childcare and Education Level 3 Cache or any similar topic only for you Order Now They can do this by providing different opportunities to individual children because each child is unique and learns differently. The practitioners’ role would therefore be to plan and resource an environment that is challenging and helps children learn in many different areas of their learning. The UN Convention on the Rights of the Child is there for the rights of children should allow children priority as they are more venerable. It states that all children’s wants and learning needs should be met. The UN Convention on the Rights of the Child has 4 cores principles and they are: Non-discrimination regardless of race, sex, gender, religion, disability and any other reason (Article 2), the best interest of the child for example; prevent child from being separated from their families unless separate on is necessary for the best interest of the child, the right to live, survival and development, freedom of speech and thought etc†¦ Article 11, 14 ; 13). Another thing as a practitioner, we need to do is promote a positive environment for parents, colleges and the children because a positive environment can mean that everyone within the setting can get a positive outcome in order to help meet the child’s needs best. Having on-going training can also benefit th e practitioners role in meeting children’s needs, teach them about childcare and can help them meet the child’s learning needs because the practitioners go on training outside the setting to get a better insight on how to work with different practitioners, adults and children. E2 Provide information about current influences on play +E4 Include examples of different theoretical models of how children play and learn. One theorist which currently influences children’s play is Jean Piaget (1948). His theory was a theory on Cognitive development. He believed that children develop in stages and that they progress through these stages in chronological order. Piaget (1948) said that there were 4 stages of development from birth to adulthood; serisori: motor- birth – 2 years, pre-operational: 2-7 years, concrete operational: 7-11/12 years, formal operations: 11/12-16 years old. He carried out a study which is called ‘mountain study’ to investigate further into his theory. This study was done in a group of children being arranged in front of a simple plaster mountain range and than he sat himself to the side and asked the children to pick from four pictures. This study showed that older children picked what Piaget (1948) saw and the younger children would pick the view they could see. When looking back at this study, Piaget (1948) found out that the older children tend to understand other peoples views. The practitioners would have a role within the Early Years setting to support the children through the different stages of development and the adults should work alongside one another to help the child develop. His theory of cognitive development is based on the importance of active discovery learning where children have child-centred classroom (Maureen D 2006). Piaget theory (1948) allows practitioners to have opportunities to learn without teaching them, appropriate activates are set up through observing the child and these activities are than suitably challenging with real experiences (Maureen D 2006). ’the balance between adult-directed play and child-initiated play should be tipped heavily in favour of child-initiative play. ’’ (Maureen D 2006). Another theorist which currently influences children’s play is Susan Isaacs (1930). She was a psychoanalyst who believed that free play indoors and outdoors is important for children’s needs, developmen t as well as helping them to learn better. She said that free play was important and necessary for children. In 1924 Susan Isaacs became the principle of Malting house, where she set up an educational experiment alongside Geoffrey Pkye(1942) to experiment with different teaching ideas on a small group of children aged two and a half to seven years. Inside the house were three interesting features; the use and development of language to promote thinking, the attention paid to children’s emotions needs and the emphasising on animosity and finding out. Piaget (1948) and Sigmund Freud (1988) were both influenced by Susan Isaacs’s (1930) theory. This theory allows children to understand what is being asked and gives the children challenge in answering a question where they can think on their own. E3- Provide information about current influences on the planning and provision Gather information about what currently influences planning and provision of learning opportunities. Every Child Matters Framework which is currently in the process to be changed is part of the Children Act 2004; it is a piece of legislation which has and influences planning and provisions of learning opportunities. The Every Child Matters ensures that settings provide quality of children’s and young people’s play and learning. This supports children from birth to 19 years. When practitioners plan, they should relate their work to the five outcomes for children; be healthy, stay safe, enjoy and achieve though learning, make a positive contribution to society and achieve economic well-being. OFSTED is a regulatory body which makes sure all childcare settings are carrying out correct planning and allowing the children to learn. This is done by having inspections which are based on the five outcomes of Every Child Matters framework. They also do this by looking at each childcare setting to see what curriculum is being offered. Each childcare setting’s curriculum will be varied and this is something the OFSTED will understand for example: every child care setting will follow the (EYFS, 2012) Early Years Foundation Stage but if a setting has children of the age of 6they would follow the National Curriculum. OFSTED requires that practitioners and workers are familiar with the relevant curriculum and requirements of OFSTED. E6 Include TWO (2) examples of information from agencies outside the settingwhich may contribute to the assessment of learning needs. You read "Unit 7 – Childcare and Education Level 3 Cache" in category "Papers" School Nurse A school nurse provides a variety of services such as undertaking health interviews and administering immunisation programmes. They can be employed by the local health authority, community trust, primary care trust or by the school directly. The responsibility of a nurse would include these roles: * Providing confidential health advice for individual children * Assessing the whole need of the school community and develop a health plan including a policy on bulling * Promoting good parenting skills by helping and supporting parents * Co-ordinating immunisation programmes Health plans for children with any disability * Providing training for school-based staff to support children with healthcare needs e. g. : asthma * Giving advice to parents, carers or school staff on childhood illnesses and the management and control of infection in the disease * Drug and alcohol abuse and smoking * Sexual health and relationship for example pregnancy * Exercise and healthy eating * Ment al health and wellbeing * Obesity * Eating disorder * Disabilities E7 Include TWO (2) plans for curriculum activities which show different approaches to planning learning opportunities E8 Include information about the importance of consulting with parents and others when planning and providing learning opportunities. It is important to consult with parents and others when planning and providing learning opportunities for the child because the parents know their child’s best interests. This is because parents are their first educators and they know what resources their child likes to use and the likes and dislike of the child. It is also important because parents you may need permission from parents in order to carry out a certain activity. Effective partnership between a childcare setting and parents will help the environment of the setting become more positive for both the child and parents using the provision. It will make the setting and parents understand each other better as well as benefit the child because the child will feel safe and want to learn and achieve better. E9 Provide evidence of current and relevant research throughout the portfolio. Evidence of current and relevant research is provided in my appendix at the end of my assignment. D1 Include an explanation of the key issues in recording assessments. D2 Include an explanation of the key issues in recording assessments. + C2 Analyse the role of assessment in informing planning and respecting learning needs. There are many important points to consider when recording assessments of children. The most important issue in recording assessments would knowing the different techniques available to use and find the one that suits most when recording the assessment of the child. These techniques maybe; written narrative, video, photographs, target child observation, checklist observation, tick charts, time sampling, event sampling and mapping to record assessments of the children. The practitioner would need to decide what type of technique would be appropriate in assessing the child and the activity carried out. When using one of the techniques the practitioner would need to check if it was reliable and valid. A technique would be good when the practitioner is able to monitor the child’s behaviour, progress and development as well as keeping them frequent and up to date. Another important factor to consider when recording assessments of children is confidentiality. C1 Analyse the importance of planning and providing learning opportunities to meet children’s diverse needs. In order to plan and provide learning opportunities to meet children’s diverse needs practitioners need to make sure that all children are included within the task and activity. This can be done by providing a large range if motivating opportunities which are accessible to all children to help them develop and allow to support them. Another thing would be a safe environment for children to learn in which is free from any discrimination and bullying. This can be done by valuing and respecting one another (children, teachers, parents and other professionals). The practitioners would be working with other professionals such as an occupational therapist to help the child have the best learning opportunities available. B1 Evaluate how the current influences on play and different theoretical models affect the planning and provision of learning opportunities. Jean Piaget’s theory influenced today’s practice as†¦ Susan Isaac’s theory influenced today’s practice as she believed that play is very important and relives freedom which allows settings to have child lead activities. Another thing she influenced was the parents and carers of the children because she showed and made practitioners aware of the fact that parents are seen as the child’s first educators and therefore they are the most important when providing learning opportunities for the child. Susan’s theory is based on working with parents and carers and this is very vital to today’s influences on play in settings which than allows practitioners to be able to plan learning opportunities for the children in their care. This can also affect planning because the practitioners may not be interacting with the children very well because they are having child lead activities and the practitioners are not experiencing what the parents and cares say about the child and how they act during the activities toward the practitioners. Research has shown thatyoung children learn best when they are actively interacting with others†¦Ã¢â‚¬ ¦. E Wood and N Bennett (1999) International Journal ofEarly Years Education 7 (1) 5-16. This affects planning because†¦Ã¢â‚¬ ¦. Discussion might also consider whether models are appropriate for all settings and factors which might be barriers to implementing change This affects planning because†¦Ã¢â‚¬ ¦. A Include a reflective account of the role of the practitioner in supporting the learning needs of children Develop the information gathered for E1 and use your experiences to consider learning needs of children and show understanding of your practice in supporting the learning needs of children. Use this reflection to suggest appropriate ways you could develop your role as a practitioner when working with children. My role as a practitioner in meeting children’s learning needs are to respect and value each individual child’s learning needs as well as understanding them. This will than allow me to provide different opportunities to individual children because ach child has individual needs and wants in the way that they learn by. Another role of mine is to plan for stimulating activities which are high in challenge to allow them to develop and learn new skills and abilities. Having a challenging environment for children allows the children to extend their learning in various styles and ways. The Equal opportunity policy is also taken into consideration by all practitioners in the setting so that all children are treated equally with respect and can enjoy and achieve their full potential. Staff ratio is also taken into account because we need enough staff in a setting to avoid accidents and keep all children safe and in a secure environment Bibliography: Books: Tassoni. Penny, Kate. Beith, Kath. Bulum and Harriet. Eldridge (2007) CACHE level 3 Child Care and Education 4th edition, London: Heinemann Marian. Beaver, Jo. Brewster, Sandy. Green, Sally. Neaum, Heidi. Sheppard, Jill. Tullack and Miranda. Walker (2008) Childcare and education Cache level 3 Cheltenham: Nelson Thorns How to cite Unit 7 – Childcare and Education Level 3 Cache, Papers

Monday, April 27, 2020

Pnin Review Essay Example

Pnin Review Paper Essay on Pnin Hapless, droll and touching ironic professor, who teaches Russian language in a small private university. This is Timofey Pnin the hero of the novel by Vladimir Nabokov A long time since I held in my hands the works of classical literature.. Perhaps that is why it was quite difficult to get used to long, flowery sentences. But the main character with a funny name Pnin subdued immediately. For some reason I always wanted to feel sorry for him, and even protect against all, do not let fall into the web of intrigue, which are weaved around him at the university. It seemed to me that just as it relates to the author himself. Â « He (Pnin) was perhaps too cautious, too wary of tricky pitfalls feared too painful as it would be strange surroundings (unpredictable America) is not pulled him into some ridiculous story. Pnin was not scattered, and the world, and Pnin had to put things in order there. I was so fascinated by the novel about the adventures of an expat in the vast New World, he did not even notice that it was morning. I then smiled and sadness together with Pnina. I reveled in the beauty of the language. And in the morning it was over. For me and for Pnina. It is hardly necessary to tell, than all these adventures have ended for Timofey Pavlovich. Well, I have left a pleasant aftertaste. Like what happens from chocolates donated by someone else. In modern books it is rare to find such a rich language that delights. Do you want to remember all of the unusual comparison like a book a gift for the bibliophile. Although, of course, this is just my humble opinion. For example, my mother can not read the works of Vladimir Nabokov. But it is impossible to please all women. A book is really very good! We will write a custom essay sample on Pnin Review specifically for you for only $16.38 $13.9/page Order now We will write a custom essay sample on Pnin Review specifically for you FOR ONLY $16.38 $13.9/page Hire Writer We will write a custom essay sample on Pnin Review specifically for you FOR ONLY $16.38 $13.9/page Hire Writer